[ÃֽŠ¿¬±¸°á°ú] Àΰ£Äڷγª¹ÙÀÌ·¯½º±º(Human Coronaviruses) ¹°Ã¼ µî ¹«»ý¹°Ç¥¸é¿¡¼ ÃÖ´ë 9ÀϱîÁö °¨¿°·Â Áö¼Ó °¡´É : ÀÌ¿¡ ´ëÇÑ È¿°úÀûÀÎ »ì±Õ ¼Òµ¶Á¦
Àΰ£Äڷγª¹ÙÀÌ·¯½º±º(Human Coronaviruses)Àº Àΰ£ ÀÌ¿Ü Çöó½ºÆ½À̳ª ±Ý¼ÓÇ¥¸é, À¯¸® µîÀÇ ¹«»ý¹° Ç¥¸é¿¡¼µµ ÀÏÁÖÀÏ¿¡¼ ÃÖ´ë 9ÀϱîÁö °¨¿°·ÂÀ» Áö¼ÓÇÒ ¼ö ÀÖÀ½À» ÃֽŠJournal of Hospital Infection 3¿ùÈ£¿¡¼ ¹àÇû´Ù. º» ¿¬±¸´Â Àΰ£Äڷγª¹ÙÀÌ·¯½º±ºÀÎ Severe Acute Respiratory Syndrome (SARS) coronavirus, Middle East Respiratory Syndrome (MERS) coronavirus or endemic human coronaviruses (HCoV) °¨¿°·ÂÀ» ¿¬±¸ÇÑ ¼±Çà °ü·Ã¿¬±¸ 22ÆíÀ» ºÐ¼®ÇÏ¿© ¹ßÇ¥ÇÑ ³»¿ëÀ¸·Î ¿ä¾àÇÏ¸é ¾Æ·¡¿Í °°´Ù.
1.Àΰ£ Äڷγª ¹ÙÀÌ·¯½º´Â ¹°Ã¼ µî ¹«»ý¹° Ç¥¸é(Inanimate surfaces)¿¡¼ ÃÖ´ë 9 ÀÏ µ¿¾È Àü¿°¼ºÀ» À¯ÁöÇÒ ¼ö ÀÖ´Ù.
2. Àΰ£ Äڷγª ¹ÙÀÌ·¯½º±º(human coronaviruses)¿¡´Â ½É°¢ÇÑ ±Þ¼º È£Èí±â ÁõÈıº (SARS) Äڷγª ¹ÙÀÌ·¯½º, Áßµ¿ È£Èí±â ÁõÈıº (MERS) Äڷγª ¹ÙÀÌ·¯½º ¶Ç´Â ¹ßº´¼º Àΰ£ Äڷγª ¹ÙÀÌ·¯½º (HCoV)¿Í °°Àº Äڷγª¹ÙÀÌ·¯½º ±ºµéÀÌ Æ÷ÇԵȴÙ.
Ç¥ 1) Persistence of coronaviruses on different types of inanimate surfaces
¾à¾î Ç®ÀÌ: MERS = Middle East Respiratory Syndrome; HCoV = human coronavirus; TGEV = transmissible gastroenteritis virus; MHV = mouse hepatitis virus; SARS = Severe Acute Respiratory Syndrome; RT = room temperature.
3. Àΰ£ Äڷγª ¹ÙÀÌ·¯½º±º(human coronaviruses)Àº ±Ý¼Ó, À¯¸® ¶Ç´Â Çöó½ºÆ½°ú °°Àº ¹«»ý¹° Ç¥¸é¿¡¼µµ ÃÖ´ë 6ÀÏ ~9ÀϱîÁö °¨¿°·ÂÀ» Áö¼Ó½Ãų ¼ö ÀÖÀ½À» È®ÀÎÇß´Ù.
Ç¥ 2) Inactivation of coronaviruses by different types of biocidal agents in carrier tests
Inactivation of coronaviruses by biocidal agents in carrier tests: Ethanol at concentrations between 62% and 71% reduced coronavirus infectivity within 1 min exposure time by 2.0–4.0 log10. Concentrations of 0.1–0.5% sodium hypochlorite and 2% glutardialdehyde were also quite effective with > 3.0 log10 reduction in viral titre. In contrast, 0.04% benzalkonium chloride, 0.06% sodium hypochlorite and 0.55% ortho-phtalaldehyde were less effective
4. Çöó½ºÆ½ µî ¹°Ã¼Ç¥¸é¿¡ ³²¾ÆÀÖ´Â Äڷγª¹ÙÀÌ·¯½º±ºÀ» »ì±ÕÇϱâ À§Çؼ´Â ¾Æ·¡ ¼Òµ¶Á¦¸¦ ÅëÇÏ¿© ÃÖ¼Ò 30ÃÊ~ÃÖ´ë 10ºÐ À̳»¿¡ Ç¥¸é¿¡ ³²¾Æ ÀÖ´Â Àΰ£ Äڷγª ¹ÙÀÌ·¯½º±º(human coronaviruses)À» ºñÈ°¼ºÈ½ÃÄÑ °¨¿°À» È¿°úÀûÀ¸·Î ºñÈ°¼ºÈ½Ãų ¼ö ÀÖ´Ù.
0.1% Â÷¾Æ¿°¼Ò»ê³ªÆ®·ý(sodium hypochlorite)
62-71% ¿¡Åº¿Ã(ethanol)
0.5% °ú»êȼö¼Ò( hydrogen peroxide)
5. Ç¥¸é¿¡ ³²¾ÆÀÖ´Â Äڷγª¹ÙÀÌ·¯½º¸¦ »ì±ÕÇϱâ À§Çؼ´Â 0.1%ÀÇ Â÷¾Æ¿°¼Ò»ê³ªÆ®·ýÀ̳ª, 62~71%ÀÇ ¿¡Å¸¿Ã·Î Ç¥¸é ¼Òµ¶Çϸé 1ºÐ ¼Òµ¶Á¦¿¡ ³ëÃâ ÈÄ, ¹°Ã¼ Ç¥¸éÀÇ Äڷγª¹ÙÀÌ·¯½º °¨¿°¼ºÀÌ Å©°Ô ÁÙ¾î µç´Ù. ÀÌ·¯ÇÑ È¿°ú´Â SARS-CoV-2¿¡ ºñ½ÁÇÑ È¿°ú¸¦ ³ªÅ¸³¾ °ÍÀ¸·Î ±â´ëÇÑ´Ù.
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References
Persistence of coronaviruses on inanimate surfaces and their inactivation with biocidal agents. (2020). J Hosp Infect. 2020 Mar;104(3):246-251. doi: 10.1016/j.jhin.2020.01.022
Transmission of SARS and MERS coronaviruses and influenza virus in healthcare settings: the possible role of dry surface contamination. (2016) J Hosp Infect. 2016 Mar;92(3):235-50. doi: 10.1016/j.jhin.2015.08.027.
From SARS coronavirus to novel animal and human coronaviruses. (2013). J Thorac Dis. 2013 Aug;5 Suppl 2:S103-8. doi: 10.3978/j.issn.2072-1439.2013.06.02.